Doom Slayer makes a gory and glorious return.
Ammo is a precious resource so you need to make sure you’re killing each demon as effectively as possible. The floating, blob-like Cacodemons can eat a lot of bullets, but launching a sticky grenade into its mouth will let you immediately Glory Kill it.
Look for these openings so you don’t burn all of your ammo at once.
Much like the sticky grenade weapon mod, precision shot is key to disabling demons’ most powerful weapons before they get a chance to use them.
Snipe the turret off the Arachnotron’s head to make it easier to approach. Blast the two rocket launchers off Revenants’ backs to keep them from blowing you up. And destroy Mancubus’ massive hand cannons as soon as you see one.
Between battles, make sure to explore to find secrets, collectibles, and Easter eggs Bethesda has sprinkled across all of the maps.
I found a hidden Dopefish from the early 90s platformer Commander Keen in Goodbye, Galaxy during the first three hours of the game. Martin promised there are a lot more where that came from.
Sentinel Crystals require you to level up two base stats (health, ammo, armor) before unlocking a perk, like adding damage to your Flame Belcher.
Runes let you unlock more powerful abilities, like slowing down time when you’re ambushing an enemy from above. You can only use three runes at a time, so choose your combinations wisely.